Glucocorticoids Affect Male Testicular Steroidogenesis
نویسندگان
چکیده
منابع مشابه
Testicular Steroidogenesis and Locomotor Activity Are Regulated by Gonadotropin-Inhibitory Hormone in Male European Sea Bass
Gonadotropin-inhibitory hormone (GnIH) is a neurohormone that suppresses reproduction by acting at both the brain and pituitary levels. In addition to the brain, GnIH may also be produced in gonads and can regulate steroidogenesis and gametogenesis. However, the function of GnIH in gonadal physiology has received little attention in fish. The main objective of this study was to evaluate the eff...
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Cadmium (Cd) is a testicular toxicant and endocrine disruptor. In the present study, we investigated the effects of maternal Cd exposure during the late pregnant period on testicular development and steroidogenesis in male offspring. Pregnant mice were injected intraperitoneally with CdCl(2) (0.5mg/kg) daily from gestational day (gd) 13 to gd 17. As expected, fetal weight and crown length were ...
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Lipopolysaccharide (LPS) is associated with adverse developmental outcomes including embryonic resorption, fetal death, congenital teratogenesis and fetal growth retardation. Here, we explored the effects of maternal LPS exposure during pregnancy on testicular development, steroidogenesis and spermatogenesis in male offspring. The pregnant mice were intraperitoneally injected with LPS (50 µg/kg...
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When a single injection of 500 I.U. of human chorionic gonadotropin (hCG) is given to rats there is an initial acute rise of plasma testosterone and of testicular content for both cyclic AMP and testosterone. This response correlates with an increase in both lyase and 17 alpha-hydroxylase activities. Thereafter both plasma and testicular testosterone decline and do not increase after a second i...
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Non-steroidal anti-inflammatory drugs (NSAIDS), of which aspirin, flurbiprofen and indomethacin are examples, exert anti-inflammatory as well as antipyretic and analgesic effects. In addition, aspirin and indomethacin have been reported to cause a reduction in fertility of male rats when applied locally to the epididymis [l ,2]. Another study shows that flurbiprofen dows not impair fertility wh...
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ژورنال
عنوان ژورنال: Physiological Research
سال: 2020
ISSN: 1802-9973,0862-8408
DOI: 10.33549/physiolres.934508